Sensitive
Osteoarthritis (hip)
CAMK2B · rs3757837
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Osteoarthritis (hip) compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Osteoarthritis (hip).
T/T
Published research associates this genotype with typical/baseline likelihood of Osteoarthritis (hip) — no copies of the reported risk allele.
Source
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
Evangelou E,
Kerkhof HJ,
Styrkarsdottir U,
Ntzani EE,
Bos SD,
Esko T,
Evans DS,
Metrustry S,
Panoutsopoulou K,
Ramos YF,
Thorleifsson G,
Tsilidis KK
and 54 more — show all
Arden N,
Aslam N,
Bellamy N,
Birrell F,
Blanco FJ,
Carr A,
Chapman K,
Day-Williams AG,
Deloukas P,
Doherty M,
Engström G,
Helgadottir HT,
Hofman A,
Ingvarsson T,
Jonsson H,
Keis A,
Keurentjes JC,
Kloppenburg M,
Lind PA,
McCaskie A,
Martin NG,
Milani L,
Montgomery GW,
Nelissen RG,
Nevitt MC,
Nilsson PM,
Ollier WE,
Parimi N,
Rai A,
Ralston SH,
Reed MR,
Riancho JA,
Rivadeneira F,
Rodriguez-Fontenla C,
Southam L,
Thorsteinsdottir U,
Tsezou A,
Wallis GA,
Wilkinson JM,
Gonzalez A,
Lane NE,
Lohmander LS,
Loughlin J,
Metspalu A,
Uitterlinden AG,
Jonsdottir I,
Stefansson K,
Slagboom PE,
Zeggini E,
Meulenbelt I,
Ioannidis JP,
Spector TD,
van Meurs JB,
Valdes AM
Annals of the rheumatic diseases · 2014 · PMID 23989986 · open access
Questions about rs3757837
What is rs3757837?
rs3757837 is a single position in the genome, in or near the CAMK2B gene. Published research associates it with osteoarthritis (hip). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3757837 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3757837 come from?
GWAS Catalog, Ann Rheum Dis 2013, PMID:23989986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants