2 4422324223222Reads by AI crawlersClaude2ChatGPT2Google · Gemini3Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls.
The effect
Each copy of the C allele carried 1.45 times the odds of Systemic lupus erythematosus; p = 1 × 10−48.
Where it sits Chromosome 7, band 7q32.1 — inside IRF5.
What each result means
C/CTwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Nature genetics · 2015 · PMID 26502338 · open access
Questions about rs3757387
What is rs3757387?
rs3757387 is a single position in the genome, in or near the IRF5 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3757387 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs3757387 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3757387 come from?
GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4422324223222Reads by AI crawlersClaude2ChatGPT2Google · Gemini3Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.