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Height

CRIM1 · rs3755206

Where this position leads

Condition: Height

rs3755206 Condition: Height Height Condition rs3755206 rs3755206 CRIM1

What the study found

Who was studied 36,227 East Asian ancestry individuals; replicated in 57,699 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.048 higher (95% confidence interval 0.03-0.066); p = 1 × 10−12.

How common The T allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 2, band 2p22.2 — in an intron of CRIM1.

What each result means

G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L
and 79 more — show all
Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L
Human molecular genetics · 2015 · PMID 25429064

Questions about rs3755206

What is rs3755206?

rs3755206 is a single position in the genome, in or near the CRIM1 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3755206 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs3755206 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3755206 come from?

GWAS Catalog, Hum Mol Genet 2014, PMID:25429064. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs3755206). MyGeneLog™. https://www.mygenelog.com/variants/rs3755206

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