Sensitive
Wilms tumor
MYCN · rs3755132
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Wilms tumor compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:22544364)
G/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Wilms tumor. (GWAS Catalog, Nat Genet 2012, PMID:22544364)
T/T
Published research associates this genotype with typical/baseline likelihood of Wilms tumor — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:22544364)
Source
A genome-wide association study identifies susceptibility loci for Wilms tumor
Turnbull C,
Perdeaux ER,
Pernet D,
Naranjo A,
Renwick A,
Seal S,
Munoz-Xicola RM,
Hanks S,
Slade I,
Zachariou A,
Warren-Perry M,
Ruark E
and 20 more — show all
Gerrard M,
Hale J,
Hewitt M,
Kohler J,
Lane S,
Levitt G,
Madi M,
Morland B,
Neefjes V,
Nicholson J,
Picton S,
Pizer B,
Ronghe M,
Stevens M,
Traunecker H,
Stiller CA,
Pritchard-Jones K,
Dome J,
Grundy P,
Rahman N
Nature genetics · 2012 · PMID 22544364 · open access
Questions about rs3755132
What is rs3755132?
rs3755132 is a single position in the genome, in or near the MYCN gene. Published research associates it with wilms tumor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3755132 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3755132 come from?
GWAS Catalog, Nat Genet 2012, PMID:22544364. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants