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Mean corpuscular hemoglobin concentration in pregnancy

PTPRC · rs3754094

What the study found

Who was studied 91,288 Chinese ancestry individuals; replicated in 44,070 Chinese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0847 higher (95% confidence interval 0.059-0.11); p = 7 × 10−11.

How common The C allele had a frequency of about 6% in the people studied.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular hemoglobin concentration in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular hemoglobin concentration in pregnancy. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular hemoglobin concentration in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs3754094

What is rs3754094?

rs3754094 is a single position in the genome, in or near the PTPRC gene. Published research associates it with mean corpuscular hemoglobin concentration in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3754094 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3754094 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin concentration in pregnancy (rs3754094). MyGeneLog™. https://www.mygenelog.com/variants/rs3754094

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