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Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256)

STN1 · rs3752946

Where this position leads

Condition: Celiac Disease

rs3752946 Condition: Celiac Disease Celiac Disease Condition rs3752946 rs3752946 STN1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0136 lower (95% confidence interval 0.0095-0.0176); p = 2 × 10−12.

How common The T allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 10, band 10q24.33 — in an intron of STN1.

What each result means

A/A No copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3752946

What is rs3752946?

rs3752946 is a single position in the genome, in or near the STN1 gene. Published research associates it with forced expiratory volume in 1 second fev1 z score (ukb data field 20256). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3752946 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs3752946 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3752946 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256) (rs3752946). MyGeneLog™. https://www.mygenelog.com/variants/rs3752946

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