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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 206,927 European ancestry men.
The effect
Each copy of the G allele shifted the measure 0.00778 higher (95% confidence interval 0.0055-0.01); p = 7 × 10−12.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 15, band 15q21.2 — in an intron of MIR4713HG.
What each result means
A/ANo copy of the version the research linked to Estradiol levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Estradiol levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Estradiol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature medicine · 2020 · PMID 32042192 · open access
Questions about rs3751591
What is rs3751591?
rs3751591 is a single position in the genome, in or near the MIR4713HG gene. Published research associates it with estradiol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3751591 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3751591 come from?
GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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