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Who was studied 684,122 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.045 lower; p = 2 × 10−38.
Where it sits Chromosome 6, band 6p22.1 — a missense change in OR12D3.
What each result means
A/ATwo copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
Communications biology · 2020 · PMID 32327693 · open access
Questions about rs3749971
What is rs3749971?
rs3749971 is a single position in the genome, in or near the OR12D3 gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3749971 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs3749971 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3749971 come from?
GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 11227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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