0 29321622319Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 603 North Indian ancestry cases, 622 North Indian ancestry controls; replicated in 733 North Indian ancestry cases, 1,148 North Indian ancestry controls.
The effect
Each copy of the A allele carried 1.97 times the odds of Ulcerative colitis (95% confidence interval 1.66-2.33); p = 2 × 10−15.
How common The A allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in a non-coding transcript of MICB-DT.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
rs3749946 is a single position in the genome, in or near the 3.8-1 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3749946 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3749946 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3749946 come from?
GWAS Catalog, Gut 2014, PMID:24837172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 29321622319Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.