Sensitive

Lung cancer

RAD52 · rs3748522

Where this position leads

Condition: Lung Cancer

rs3748522 Condition: Lung Cancer Lung Cancer Condition rs3748522 rs3748522 RAD52

What the study found

Who was studied 22,299 East Asian ancestry cases, 225,690 East Asian ancestry controls, 31,351 European ancestry cases, 260,520 European ancestry controls.

The effect Each copy of the A allele carried 0.95 times the odds of Lung cancer (95% confidence interval 0.93-0.96); p = 4 × 10−9.

How common The A allele had a frequency of about 56% in the people studied.

Where it sits Chromosome 12, band 12p13.33 — in an intron of RAD52.

What each result means

A/A Two copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Lung cancer. That is a smaller link than two copies.
C/C No copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.
Source

Questions about rs3748522

What is rs3748522?

rs3748522 is a single position in the genome, in or near the RAD52 gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3748522 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs3748522 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3748522 come from?

GWAS Catalog, Genome medicine 2026, PMID:42152146. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung cancer (rs3748522). MyGeneLog™. https://www.mygenelog.com/variants/rs3748522

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