Venous thromboembolism recurrence in provoked as first VTE
near ARL17B · rs3744462
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Who was studied 772 European ancestry cases, 2,142 European ancestry controls.
The effect
Each copy of the G allele carried 2.57 times the odds of Venous thromboembolism recurrence in provoked as first VTE (95% confidence interval 1.908999-3.453684); p = 5 × 10−10.
How common The G allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 17, band 17q21.31 — between genes, 6.8 kb from ARL17B.
What each result means
C/CNo copy of the version the research linked to Venous thromboembolism recurrence in provoked as first VTE. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Venous thromboembolism recurrence in provoked as first VTE. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Venous thromboembolism recurrence in provoked as first VTE. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3744462 is a single position in the genome, in or near the near ARL17B gene. Published research associates it with venous thromboembolism recurrence in provoked as first vte. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3744462 linked to?
On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs3744462 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3744462 come from?
GWAS Catalog, Blood 2025, PMID:40811855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Venous thromboembolism recurrence in provoked as first VTE (rs3744462). MyGeneLog™. https://www.mygenelog.com/variants/rs3744462