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White matter hyperintensity volume

TRIM47 · rs3744020

What the study found

Who was studied 8,429 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.109 higher (95% confidence interval 0.078-0.140); p = 4 × 10−11.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 17, band 17q25.1 — in an intron of TRIM47.

What each result means

A/A Two copies of the version the research linked to White matter hyperintensity volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to White matter hyperintensity volume. That is a smaller link than two copies.
G/G No copy of the version the research linked to White matter hyperintensity volume. This is the starting point the study compared everyone against.
Source

Questions about rs3744020

What is rs3744020?

rs3744020 is a single position in the genome, in or near the TRIM47 gene. Published research associates it with white matter hyperintensity volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3744020 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3744020 come from?

GWAS Catalog, Stroke 2018, PMID:29752348. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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White matter hyperintensity volume (rs3744020). MyGeneLog™. https://www.mygenelog.com/variants/rs3744020

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