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Intracranial aneurysm

STARD13 · rs3742321

Where this position leads

Condition: Intracranial Aneurysm

rs3742321 Condition: Intracranial Aneurysm Intracranial Aneurysm Condition rs3742321 rs3742321 STARD13

What the study found

Who was studied 7,495 European ancestry cases, 3,259 East Asian ancestry cases, 71,934 European ancestry controls, 234,948 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.144 lower (95% confidence interval 0.11-0.18); p = 5 × 10−15.

How common The T allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 13, band 13q13.1 — a missense change in STARD13.

What each result means

C/C No copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3742321

What is rs3742321?

rs3742321 is a single position in the genome, in or near the STARD13 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3742321 linked to?

On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.

Does having rs3742321 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3742321 come from?

GWAS Catalog, Nature genetics 2020, PMID:33199917. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Intracranial aneurysm (rs3742321). MyGeneLog™. https://www.mygenelog.com/variants/rs3742321

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