Alzheimer's disease or family history of Alzheimer's disease
RGS6 · rs374043832
0 2052211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,559 Hispanic cases, 5,908 Hispanic controls, 996 African ancestry cases, 1,134 African ancestry controls, 1,100 Admixed-American ancestry cases, 31,755 Admixed-American ancestry controls, 7,077 European ancestry cases, 65 European ancestry controls, 285 East or South Asian cases, 2,266 East or South Asian controls, 21 Middle-Eastern ancestry cases, 94 Middle-Eastern ancestry controls.
The effect
Each copy of the A allele carried 5.40 times the odds of Alzheimer's disease or family history of Alzheimer's disease (95% confidence interval 3.0-9.8); p = 3 × 10−8.
Where it sits Chromosome 14, band 14q24.2 — in an intron of RGS6.
What each result means
A/ATwo copies of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. This is the starting point the study compared everyone against.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026 · PMID 41755704 · open access
Questions about rs374043832
What is rs374043832?
rs374043832 is a single position in the genome, in or near the RGS6 gene. Published research associates it with alzheimer's disease or family history of alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs374043832 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs374043832 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs374043832 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2026, PMID:41755704. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2052211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Alzheimer's disease or family history of Alzheimer's disease (rs374043832). MyGeneLog™. https://www.mygenelog.com/variants/rs374043832