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Intracranial aneurysm

FMO4 · rs3737926

Where this position leads

Condition: Intracranial Aneurysm

rs3737926 Condition: Intracranial Aneurysm Intracranial Aneurysm Condition rs3737926 rs3737926 FMO4

What the study found

Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.

The effect Each copy of the C allele carried 2.78 times the odds of Intracranial aneurysm (95% confidence interval 2-3.7); p = 2 × 10−10.

How common The C allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — a synonymous change in FMO4.

What each result means

C/C Two copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
T/T No copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
Source

Questions about rs3737926

What is rs3737926?

rs3737926 is a single position in the genome, in or near the FMO4 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3737926 linked to?

On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.

Does having rs3737926 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3737926 come from?

GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Intracranial aneurysm (rs3737926). MyGeneLog™. https://www.mygenelog.com/variants/rs3737926

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