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Who was studied 672 Korean ancestry cases, 3,700 Korean ancestry controls; replicated in 200 Korean ancestry cases, 1,812 Korean ancestry controls.
The effect
Each copy of the A allele carried 1.48 times the odds of Early onset atrial fibrillation (95% confidence interval 1.31-1.68); p = 2 × 10−9.
How common The A allele had a frequency of about 68% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — in an intron of LOC105371687.
What each result means
A/ATwo copies of the version the research linked to Early onset atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Early onset atrial fibrillation. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Early onset atrial fibrillation. This is the starting point the study compared everyone against.
rs3737883 is a single position in the genome, in or near the PPFIA4 gene. Published research associates it with early onset atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3737883 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs3737883 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3737883 come from?
GWAS Catalog, Eur Heart J 2017, PMID:28460022. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 343213822319Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity3Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total34Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Early onset atrial fibrillation (rs3737883). MyGeneLog™. https://www.mygenelog.com/variants/rs3737883