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N-palmitoylglycine levels

NSUN4 · rs3737744

What the study found

Who was studied 8,809 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.149 lower (95% confidence interval 0.12-0.18); p = 4 × 10−20.

Where it sits Chromosome 1, band 1p33 — a missense change in NSUN4.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of N-palmitoylglycine levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with N-palmitoylglycine levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of N-palmitoylglycine levels compared to the general population.
Source

Questions about rs3737744

What is rs3737744?

rs3737744 is a single position in the genome, in or near the NSUN4 gene. Published research associates it with n-palmitoylglycine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3737744 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3737744 come from?

GWAS Catalog, Metabolites 2022, PMID:35050183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

N-palmitoylglycine levels (rs3737744). MyGeneLog™. https://www.mygenelog.com/variants/rs3737744

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