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Carbohydrate sulfotransferase 12 levels

CHST12 · rs3735099

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.452 higher (95% confidence interval 0.35-0.56); p = 1 × 10−16.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 7, band 7p22.3 — a missense change in CHST12.

What each result means

A/A Two copies of the version the research linked to Carbohydrate sulfotransferase 12 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Carbohydrate sulfotransferase 12 levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Carbohydrate sulfotransferase 12 levels. This is the starting point the study compared everyone against.
Source

Questions about rs3735099

What is rs3735099?

rs3735099 is a single position in the genome, in or near the CHST12 gene. Published research associates it with carbohydrate sulfotransferase 12 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3735099 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3735099 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Carbohydrate sulfotransferase 12 levels (rs3735099). MyGeneLog™. https://www.mygenelog.com/variants/rs3735099

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