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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 39,893 European or unknown ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0362 lower (95% confidence interval 0.024-0.048); p = 1 × 10−9.
How common The A allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 4, band 4q21.21 — in the 3′ untranslated region of FGF5.
What each result means
A/ATwo copies of the version the research linked to Descending aorta diameter. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Descending aorta diameter. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Descending aorta diameter. This is the starting point the study compared everyone against.
Journal of the American College of Cardiology · 2023 · PMID 37019578
Questions about rs3733336
What is rs3733336?
rs3733336 is a single position in the genome, in or near the FGF5 gene. Published research associates it with descending aorta diameter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3733336 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3733336 come from?
GWAS Catalog, Journal of the American College of Cardiology 2023, PMID:37019578. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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