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Who was studied 41,917 European ancestry bipolar disorder cases, 12,366 European ancestry ulcerative colitis cases, 405,158 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.014 lower (95% confidence interval 0.01-0.018); p = 1 × 10−10.
Where it sits Chromosome 3, band 3p22.2 — in an intron of TRANK1.
What each result means
A/ANo copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of affective disorders · 2024 · PMID 38154582
Questions about rs3732385
What is rs3732385?
rs3732385 is a single position in the genome, in or near the TRANK1 gene. Published research associates it with bipolar disorder or ulcerative colitis (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3732385 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3732385 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3732385 come from?
GWAS Catalog, Journal of affective disorders 2024, PMID:38154582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Bipolar disorder or ulcerative colitis (MTAG) (rs3732385). MyGeneLog™. https://www.mygenelog.com/variants/rs3732385