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Who was studied 309 African American or Afro-Caribbean cases, 55,196 African American or Afro-Caribbean controls, 1,102 European ancestry cases, 314,566 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 3.85 lower (95% confidence interval 3.83-3.86); p = 6 × 10−12.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 20, band 20p12.3 — in an intron of PLCB1.
What each result means
A/ANo copy of the version the research linked to Biological Father: Schizophrenia. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Biological Father: Schizophrenia. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Biological Father: Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs373182523
What is rs373182523?
rs373182523 is a single position in the genome, in or near the PLCB1 gene. Published research associates it with biological father: schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs373182523 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs373182523 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs373182523 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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