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Omega-3 fatty acids to Omega-6 fatty acids ratio

MYBPC3 · rs3729986

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 9 × 10−11.

Where it sits Chromosome 11, band 11p11.2 — a missense change in MYBPC3.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Omega-3 fatty acids to Omega-6 fatty acids ratio — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Omega-3 fatty acids to Omega-6 fatty acids ratio.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Omega-3 fatty acids to Omega-6 fatty acids ratio compared to the general population.
Source

Questions about rs3729986

What is rs3729986?

rs3729986 is a single position in the genome, in or near the MYBPC3 gene. Published research associates it with omega-3 fatty acids to omega-6 fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3729986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3729986 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Omega-3 fatty acids to Omega-6 fatty acids ratio (rs3729986). MyGeneLog™. https://www.mygenelog.com/variants/rs3729986

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