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white blood cell count (WBC, mean, inv-norm transformed)

DBN1 · rs371071053

What the study found

Who was studied 108,896 African American or Afro-Caribbean individuals.

The effect Each copy of the C allele shifted the measure 0.421 lower (95% confidence interval 0.35-0.49); p = 5 × 10−32.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 5, band 5q35.3 — in the 5′ untranslated region of DBN1.

What each result means

C/C Two copies of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). This is the starting point the study compared everyone against.
Source

Questions about rs371071053

What is rs371071053?

rs371071053 is a single position in the genome, in or near the DBN1 gene. Published research associates it with white blood cell count (wbc, mean, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs371071053 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs371071053 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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white blood cell count (WBC, mean, inv-norm transformed) (rs371071053). MyGeneLog™. https://www.mygenelog.com/variants/rs371071053

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