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Methylmalonate (mma) levels

near ZNF778 · rs370792676

What the study found

Who was studied 6,136 Finnish ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.44 lower; p = 5 × 10−12.

Where it sits Chromosome 16, band 16q24.3 — between genes, 10.9 kb from ZNF778.

What each result means

A/A No copy of the version the research linked to Methylmalonate (mma) levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Methylmalonate (mma) levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Methylmalonate (mma) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs370792676

What is rs370792676?

rs370792676 is a single position in the genome, in or near the near ZNF778 gene. Published research associates it with methylmalonate (mma) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs370792676 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs370792676 come from?

GWAS Catalog, Nature communications 2022, PMID:35347128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Methylmalonate (mma) levels (rs370792676). MyGeneLog™. https://www.mygenelog.com/variants/rs370792676

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