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Inguinal hernia

ADAMTS6 · rs370763

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Inguinal hernia compared to the general population.

A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Inguinal hernia.

T/T Published research associates this genotype with typical/baseline likelihood of Inguinal hernia — no copies of the reported risk allele.

Source

A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia

Jorgenson E, Makki N, Shen L, Chen DC, Tian C, Eckalbar WL, Hinds D, Ahituv N, Avins A

Nature communications · 2015 · PMID 26686553 · open access

Questions about rs370763

What is rs370763?

rs370763 is a single position in the genome, in or near the ADAMTS6 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs370763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs370763 come from?

GWAS Catalog, Nat Commun 2015, PMID:26686553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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