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Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0285 lower (95% confidence interval 0.021-0.036); p = 6 × 10−13.
How common The A allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 6, band 6p21.1 — in the 3′ untranslated region of MRPL2.
What each result means
A/ATwo copies of the version the research linked to Haemoglobin concentration (UKB data field 30020). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Haemoglobin concentration (UKB data field 30020). That is a smaller link than two copies.
C/CNo copy of the version the research linked to Haemoglobin concentration (UKB data field 30020). This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs370058840
What is rs370058840?
rs370058840 is a single position in the genome, in or near the MRPL2 gene. Published research associates it with haemoglobin concentration (ukb data field 30020). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs370058840 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs370058840 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs370058840 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Haemoglobin concentration (UKB data field 30020) (rs370058840). MyGeneLog™. https://www.mygenelog.com/variants/rs370058840