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Reticulocyte count

near OR10K2 · rs369186418

Where this position leads

Condition: Blood Cell Counts

rs369186418 Condition: Blood Cell Counts Blood Cell Counts Condition rs369186418 rs369186418 near OR10K2

What the study found

Who was studied 170,641 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.152 higher (95% confidence interval 0.11-0.2); p = 7 × 10−12.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q23.1 — between genes, 3.4 kb from OR10K2.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Reticulocyte count — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Reticulocyte count.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Reticulocyte count compared to the general population.
Source

Questions about rs369186418

What is rs369186418?

rs369186418 is a single position in the genome, in or near the near OR10K2 gene. Published research associates it with reticulocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs369186418 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs369186418 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs369186418 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Reticulocyte count (rs369186418). MyGeneLog™. https://www.mygenelog.com/variants/rs369186418

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