Gene Knowledge Graph
UTC
Sensitive

Takes medication for parkinson's disease?

near H2ACP1 · rs368657122

Where this position leads

Condition: Parkinson's Disease

rs368657122 Condition: Parkinson's Disease Parkinson's Disease Condition rs368657122 rs368657122 near H2ACP1

What the study found

Who was studied 351 African American or Afro-Caribbean cases, 55,154 African American or Afro-Caribbean controls, 3,573 European ancestry cases, 312,095 European ancestry controls, 259 Hispanic or Latin American cases, 29,055 Hispanic or Latin American controls.

The effect Each copy of the G allele shifted the measure 1.63 lower (95% confidence interval 1.56-1.71); p = 9 × 10−12.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 13, band 13q13.3 — between genes, 42.4 kb from H2ACP1.

What each result means

A/A No copy of the version the research linked to Takes medication for parkinson's disease?. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Takes medication for parkinson's disease?. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Takes medication for parkinson's disease?. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F
and 59 more — show all
Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Kripke CM, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Shakt G, Sun YV, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano JM, Madduri RK, Damrauer S, Liao KP
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access

Questions about rs368657122

What is rs368657122?

rs368657122 is a single position in the genome, in or near the near H2ACP1 gene. Published research associates it with takes medication for parkinson's disease?. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs368657122 linked to?

On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs368657122 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs368657122 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Takes medication for parkinson's disease? (rs368657122). MyGeneLog™. https://www.mygenelog.com/variants/rs368657122

← See all variants