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High-density lipoprotein levels (MTAG)

IGLJCOR18 · rs367848985

What the study found

Who was studied 125,000 African ancestry individuals (MTAG boosted by total cholesterol and triglyceride samples).

The effect Each copy of the C allele shifted the measure 0.32 higher (95% confidence interval 0.22-0.42); p = 7 × 10−10.

Where it sits Chromosome 18, band 18p11.31 — in a non-coding transcript of IGLJCOR18.

What each result means

C/C Two copies of the version the research linked to High-density lipoprotein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to High-density lipoprotein levels (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to High-density lipoprotein levels (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs367848985

What is rs367848985?

rs367848985 is a single position in the genome, in or near the IGLJCOR18 gene. Published research associates it with high-density lipoprotein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs367848985 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs367848985 come from?

GWAS Catalog, Nature communications 2023, PMID:37669986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High-density lipoprotein levels (MTAG) (rs367848985). MyGeneLog™. https://www.mygenelog.com/variants/rs367848985

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