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Psoriasis

PRM3 · rs367569

Where this position leads

Condition: Psoriasis

rs367569 Condition: Psoriasis Psoriasis Condition rs367569 rs367569 PRM3

What the study found

Who was studied 10,588 European ancestry cases, 22,806 European ancestry controls.

The effect Each copy of the C allele carried 1.13 times the odds of Psoriasis (95% confidence interval -); p = 5 × 10−8.

How common The C allele had a frequency of about 71% in the people studied.

Where it sits Chromosome 16, band 16p13.13 — inside LOC105371082.

What each result means

C/C Two copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
Source

Questions about rs367569

What is rs367569?

rs367569 is a single position in the genome, in or near the PRM3 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs367569 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs367569 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs367569 come from?

GWAS Catalog, Nat Genet 2012, PMID:23143594. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (rs367569). MyGeneLog™. https://www.mygenelog.com/variants/rs367569

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