Standard

Sleep duration

SLC6A3 · rs365663

Where this position leads

Condition: Sleep and Circadian Rhythm

rs365663 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs365663 rs365663 SLC6A3

What the study found

Who was studied 384,317 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0167 lower (95% confidence interval 0.012-0.022); p = 1 × 10−11.

How common The G allele had a frequency of about 46% in the people studied.

Where it sits Chromosome 5, band 5p15.33 — in an intron of SLC6A3.

What each result means

A/A No copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs365663

What is rs365663?

rs365663 is a single position in the genome, in or near the SLC6A3 gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs365663 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs365663 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs365663 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (rs365663). MyGeneLog™. https://www.mygenelog.com/variants/rs365663

← See all variants