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NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (NDUFS4.10584.7.3)

near CFHR3 · rs365299

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.68 higher (95% confidence interval 0.62-0.74); p = 1 × 10−155.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 1, band 1q31.3 — between genes, 8.2 kb from CFHR3.

What each result means

C/C No copy of the version the research linked to NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (NDUFS4.10584.7.3). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (NDUFS4.10584.7.3). That is a smaller link than two copies.
T/T Two copies of the version the research linked to NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (NDUFS4.10584.7.3). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs365299

What is rs365299?

rs365299 is a single position in the genome, in or near the near CFHR3 gene. Published research associates it with nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (ndufs4.10584.7.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs365299 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs365299 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial levels (NDUFS4.10584.7.3) (rs365299). MyGeneLog™. https://www.mygenelog.com/variants/rs365299

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