0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Its strongest genetic-study result is p = 10−16, with 1 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 472,730 East Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0298 lower (95% confidence interval 0.023-0.037); p = 8 × 10−17.
How common The G allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 15, band 15q21.1 — at a splice region of FBN1.
What ClinVar records
ClassificationBenign/Likely benign for Familial thoracic aortic aneurysm and aortic dissection, Stiff skin syndrome, Acromicric dysplasia, Geleophysic dysplasia, Marfan syndrome and 3 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 15 submitters), last evaluated 2026-02-04.
ClinVar record 42433NM_000138.5(FBN1):c.7819+8A>C
Change history
MyGeneLog™ keeps a copy of every weekly release from 2026-10-19 and compares them. This position's classification has not changed since.
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
G/GTwo copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Height. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Height. This is the starting point the study compared everyone against.
rs363838 is a single position in the genome, in or near the FBN1 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs363838 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs363838 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs363838 come from?
GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.