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Waist-to-hip ratio adjusted for BMI

RAB26 · rs36232

What the study found

Who was studied 660,648 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.015 higher (95% confidence interval 0.01-0.02); p = 3 × 10−10.

How common The G allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — in an intron of RAB26.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-to-hip ratio adjusted for BMI compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-to-hip ratio adjusted for BMI.
T/T Published research associates this genotype with typical/baseline likelihood of Waist-to-hip ratio adjusted for BMI — no copies of the reported risk allele.
Source

Questions about rs36232

What is rs36232?

rs36232 is a single position in the genome, in or near the RAB26 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs36232 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs36232 come from?

GWAS Catalog, JAMA 2018, PMID:30575882. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs36232). MyGeneLog™. https://www.mygenelog.com/variants/rs36232

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