Squamous cell lung carcinoma (conditioned on cigarettes per day)
CHUK-DT · rs36229791
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 8,901 European ancestry cases, 64,477 European ancestry controls, 300 African ancestry cases, 62,112 African ancestry controls; replicated in 4,162 European ancestry cases, 13,599 European ancestry controls, 451 African ancestry cases, 3,779 African ancestry controls.
The effect
Each copy of the A allele carried 1.25 times the odds of Squamous cell lung carcinoma (conditioned on cigarettes per day) (95% confidence interval 1.169-1.336); p = 6 × 10−11.
How common The A allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 10, band 10q24.31 — in an intron of CHUK-DT.
What each result means
A/ATwo copies of the version the research linked to Squamous cell lung carcinoma (conditioned on cigarettes per day). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Squamous cell lung carcinoma (conditioned on cigarettes per day). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Squamous cell lung carcinoma (conditioned on cigarettes per day). This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39366959 · open access
Questions about rs36229791
What is rs36229791?
rs36229791 is a single position in the genome, in or near the CHUK-DT gene. Published research associates it with squamous cell lung carcinoma (conditioned on cigarettes per day). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs36229791 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs36229791 come from?
GWAS Catalog, Nature communications 2024, PMID:39366959. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Squamous cell lung carcinoma (conditioned on cigarettes per day) (rs36229791). MyGeneLog™. https://www.mygenelog.com/variants/rs36229791