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Cervical dysplasia

HLA-DQA1 · rs36214159

What the study found

Who was studied 14,694 European ancestry cases, 150,563 European ancestry controls.

The effect Each copy of the G allele carried 0.79 times the odds of Cervical dysplasia (95% confidence interval 0.76-0.83); p = 2 × 10−22.

How common The G allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — inside HLA-DQA1.

What each result means

G/G Two copies of the version the research linked to Cervical dysplasia. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Cervical dysplasia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Cervical dysplasia. This is the starting point the study compared everyone against.
Source

Questions about rs36214159

What is rs36214159?

rs36214159 is a single position in the genome, in or near the HLA-DQA1 gene. Published research associates it with cervical dysplasia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs36214159 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs36214159 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36929174. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cervical dysplasia (rs36214159). MyGeneLog™. https://www.mygenelog.com/variants/rs36214159

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