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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 56,912 Chinese ancestry females; replicated in up to 20,026 East Asian ancestry females.
The effect
Each copy of the A allele shifted the measure 0.109 higher (95% confidence interval 0.095-0.123); p = 3 × 10−56.
Where it sits Chromosome 5, band 5q15 — in an intron of CAST.
What each result means
A/ATwo copies of the version the research linked to Fasting plasma glucose. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Fasting plasma glucose. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Fasting plasma glucose. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40325049 · open access
Questions about rs36115340
What is rs36115340?
rs36115340 is a single position in the genome, in or near the CAST gene. Published research associates it with fasting plasma glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs36115340 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs36115340 come from?
GWAS Catalog, Nature communications 2025, PMID:40325049. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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