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Hypertension

FGF5 · rs36034102

Where this position leads

Condition: Resistant Hypertension

rs36034102 Condition: Resistant Hypertension Resistant Hypertension Condition rs36034102 rs36034102 FGF5

What the study found

Who was studied 8,178 Korean ancestry cases, 9,558 Korean ancestry controls.

The effect Each copy of the T allele carried 1.22 times the odds of Hypertension (95% confidence interval 1.15-1.29); p = 3 × 10−12.

How common The T allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — in an intron of FGF5.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Hypertension — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hypertension.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hypertension compared to the general population.
Source
Identifying Interactions between Dietary Sodium, Potassium, Sodium-Potassium Ratios, and <i>FGF5</i> rs16998073 Variants and Their Associated Risk for Hypertension in Korean Adults
Jeong H, Jin HS, Kim SS, Shin D
Nutrients · 2020 · PMID 32709000 · open access

Questions about rs36034102

What is rs36034102?

rs36034102 is a single position in the genome, in or near the FGF5 gene. Published research associates it with hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs36034102 linked to?

On MyGeneLog this position is linked to Resistant Hypertension. The research behind each link, and its sources, are set out on that condition page.

Does having rs36034102 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs36034102 come from?

GWAS Catalog, Nutrients 2020, PMID:32709000. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypertension (rs36034102). MyGeneLog™. https://www.mygenelog.com/variants/rs36034102

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