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Facial wrinkles (crow's feet)

FARSB · rs36015125

What the study found

Who was studied 11,079 Korean ancestry individuals; replicated in 5,940 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.89 higher; p = 2 × 10−11.

How common The C allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 2, band 2q36.1 — in an intron of FARSB.

What each result means

C/C Two copies of the version the research linked to Facial wrinkles (crow's feet). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Facial wrinkles (crow's feet). That is a smaller link than two copies.
G/G No copy of the version the research linked to Facial wrinkles (crow's feet). This is the starting point the study compared everyone against.
Source

Questions about rs36015125

What is rs36015125?

rs36015125 is a single position in the genome, in or near the FARSB gene. Published research associates it with facial wrinkles (crow's feet). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs36015125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs36015125 come from?

GWAS Catalog, The Journal of investigative dermatology 2022, PMID:35421404. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Facial wrinkles (crow's feet) (rs36015125). MyGeneLog™. https://www.mygenelog.com/variants/rs36015125

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