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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 288,127 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0547 higher (95% confidence interval 0.047-0.062); p = 1 × 10−46.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 12, band 12q24.31 — between genes, 1.9 kb from SCARB1.
What each result means
A/ATwo copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36333282 · open access
Questions about rs35950463
What is rs35950463?
rs35950463 is a single position in the genome, in or near the near SCARB1 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35950463 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35950463 come from?
GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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