Standard

Urinary albumin excretion

SPHKAP · rs35924503

Where this position leads

Condition: Kidney Function

rs35924503 Condition: Kidney Function Kidney Function Condition rs35924503 rs35924503 SPHKAP

What the study found

Who was studied 382,500 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.247 higher (95% confidence interval 0.2-0.3); p = 9 × 10−23.

How common The C allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 2, band 2q36.3 — between genes, 84.9 kb from SPHKAP.

What each result means

C/C Two copies of the version the research linked to Urinary albumin excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Urinary albumin excretion. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urinary albumin excretion. This is the starting point the study compared everyone against.
Source

Questions about rs35924503

What is rs35924503?

rs35924503 is a single position in the genome, in or near the SPHKAP gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35924503 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs35924503 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35924503 come from?

GWAS Catalog, Am J Hum Genet 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Urinary albumin excretion (rs35924503). MyGeneLog™. https://www.mygenelog.com/variants/rs35924503

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