Standard

Weight

near REXO1 · rs35917007

Where this position leads

Condition: Obesity and Body Weight

rs35917007 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs35917007 rs35917007 near REXO1

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0097 lower (95% confidence interval 0.007-0.0124); p = 3 × 10−12.

Where it sits Chromosome 19, band 19p13.3 — between genes, 0.7 kb from REXO1.

What each result means

A/A Two copies of the version the research linked to Weight. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Weight. That is a smaller link than two copies.
G/G No copy of the version the research linked to Weight. This is the starting point the study compared everyone against.
Source

Questions about rs35917007

What is rs35917007?

rs35917007 is a single position in the genome, in or near the near REXO1 gene. Published research associates it with weight. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35917007 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs35917007 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35917007 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Weight (rs35917007). MyGeneLog™. https://www.mygenelog.com/variants/rs35917007

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