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MPO protein levels

MPO · rs35897051

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 1.13 lower (95% confidence interval 1.05-1.2); p = 7 × 10−221.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 17, band 17q22 — inside MPO.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of MPO protein levels compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with MPO protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of MPO protein levels — no copies of the reported risk allele.
Source

Questions about rs35897051

What is rs35897051?

rs35897051 is a single position in the genome, in or near the MPO gene. Published research associates it with mpo protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35897051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35897051 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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MPO protein levels (rs35897051). MyGeneLog™. https://www.mygenelog.com/variants/rs35897051

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