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Testosterone levels

POLR2A · rs35894069

What the study found

Who was studied 4,291 European ancestry men, 3,352 European ancestry women.

The effect Each copy of the A allele shifted the measure 0.0691 higher (95% confidence interval 0.047-0.091); p = 5 × 10−10.

How common The A allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of POLR2A.

What each result means

A/A Two copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
Source

Questions about rs35894069

What is rs35894069?

rs35894069 is a single position in the genome, in or near the POLR2A gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35894069 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35894069 come from?

GWAS Catalog, The Journal of clinical endocrinology and metabolism 2019, PMID:31169883. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Testosterone levels (rs35894069). MyGeneLog™. https://www.mygenelog.com/variants/rs35894069

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