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Vitamin D levels

near SLC4A4 · rs35887244

Where this position leads

Condition: Gout

rs35887244 Condition: Gout Gout Condition rs35887244 rs35887244 near SLC4A4

What the study found

Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0572 lower (95% confidence interval 0.05-0.064); p = 9 × 10−57.

Where it sits Chromosome 4, band 4q13.3 — between genes, 17.9 kb from SLC4A4.

What each result means

C/C Two copies of the version the research linked to Vitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Vitamin D levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vitamin D levels. This is the starting point the study compared everyone against.
Source

Questions about rs35887244

What is rs35887244?

rs35887244 is a single position in the genome, in or near the near SLC4A4 gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35887244 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs35887244 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35887244 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin D levels (rs35887244). MyGeneLog™. https://www.mygenelog.com/variants/rs35887244

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