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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,301,549 European ancestry cases, 1,160,583 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0188 lower (95% confidence interval 0.013-0.025); p = 9 × 10−11.
Where it sits Chromosome 4, band 4p15.1 — between genes, 43.6 kb from RPL31P31.
What each result means
C/CNo copy of the version the research linked to Biological sex. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Biological sex. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Biological sex. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs35883430 is a single position in the genome, in or near the near RPL31P31 gene. Published research associates it with biological sex. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35883430 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35883430 come from?
GWAS Catalog, Nature genetics 2021, PMID:33888908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Biological sex (rs35883430). MyGeneLog™. https://www.mygenelog.com/variants/rs35883430