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Eosinophil count

KLRG1 · rs35870866

What the study found

Who was studied 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0122 lower (95% confidence interval 0.0091-0.0153); p = 1 × 10−13.

Where it sits Chromosome 12, band 12p13.31 — inside KLRG1.

What each result means

A/A Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
C/C No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
Source

Questions about rs35870866

What is rs35870866?

rs35870866 is a single position in the genome, in or near the KLRG1 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35870866 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35870866 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs35870866). MyGeneLog™. https://www.mygenelog.com/variants/rs35870866

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