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Hemoglobin concentration

SBF2 · rs35815123

What the study found

Who was studied 46,904 European ancestry males; replicated in 80,822 European ancestry males.

The effect Each copy of the A allele shifted the measure 0.0338 lower; p = 3 × 10−12.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of SBF2.

What each result means

A/A Two copies of the version the research linked to Hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hemoglobin concentration. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hemoglobin concentration. This is the starting point the study compared everyone against.
Source

Questions about rs35815123

What is rs35815123?

rs35815123 is a single position in the genome, in or near the SBF2 gene. Published research associates it with hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35815123 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35815123 come from?

GWAS Catalog, The Journal of nutritional biochemistry 2023, PMID:35964923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin concentration (rs35815123). MyGeneLog™. https://www.mygenelog.com/variants/rs35815123

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