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Who was studied 235,256 European ancestry individuals; replicated in 100,764 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 5 × 10−118.
How common The A allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 17, band 17q11.2 — in an intron of TAOK1.
What each result means
A/ATwo copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Platelet count. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
American journal of human genetics · 2021 · PMID 34469753
Questions about rs35763383
What is rs35763383?
rs35763383 is a single position in the genome, in or near the TAOK1 gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35763383 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs35763383 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35763383 come from?
GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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