Standard
Number of sexual partners
TMEM161B · rs357508
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Number of sexual partners compared to the general population.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Number of sexual partners.
C/C
Published research associates this genotype with typical/baseline likelihood of Number of sexual partners — no copies of the reported risk allele.
Source
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Karlsson Linnér R,
Biroli P,
Kong E,
Meddens SFW,
Wedow R,
Fontana MA,
Lebreton M,
Tino SP,
Abdellaoui A,
Hammerschlag AR,
Nivard MG,
Okbay A
and 80 more — show all
Rietveld CA,
Timshel PN,
Trzaskowski M,
Vlaming R,
Zünd CL,
Bao Y,
Buzdugan L,
Caplin AH,
Chen CY,
Eibich P,
Fontanillas P,
Gonzalez JR,
Joshi PK,
Karhunen V,
Kleinman A,
Levin RZ,
Lill CM,
Meddens GA,
Muntané G,
Sanchez-Roige S,
Rooij FJV,
Taskesen E,
Wu Y,
Zhang F,
Auton A,
Boardman JD,
Clark DW,
Conlin A,
Dolan CC,
Fischbacher U,
Groenen PJF,
Harris KM,
Hasler G,
Hofman A,
Ikram MA,
Jain S,
Karlsson R,
Kessler RC,
Kooyman M,
MacKillop J,
Männikkö M,
Morcillo-Suarez C,
McQueen MB,
Schmidt KM,
Smart MC,
Sutter M,
Thurik AR,
Uitterlinden AG,
White J,
Wit H,
Yang J,
Bertram L,
Boomsma DI,
Esko T,
Fehr E,
Hinds DA,
Johannesson M,
Kumari M,
Laibson D,
Magnusson PKE,
Meyer MN,
Navarro A,
Palmer AA,
Pers TH,
Posthuma D,
Schunk D,
Stein MB,
Svento R,
Tiemeier H,
Timmers PRHJ,
Turley P,
Ursano RJ,
Wagner GG,
Wilson JF,
Gratten J,
Lee JJ,
Cesarini D,
Benjamin DJ,
Koellinger PD,
Beauchamp JP
Nature genetics · 2019 · PMID 30643258
Questions about rs357508
What is rs357508?
rs357508 is a single position in the genome, in or near the TMEM161B gene. Published research associates it with number of sexual partners. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs357508 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs357508 come from?
GWAS Catalog, Nat Genet 2019, PMID:30643258. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants